WebDec 1, 2024 · CircWHSC1 was a sponge of miR-212-5p in TNBC cells. (A) The subcellular localization of circWHSC1 in TNBC cells was determined by qRT-PCR. (B) The binding … WebDec 1, 2024 · CircWHSC1 overexpressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR‐646, which was confirmed using luciferase reporter gene assays.
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WebIntroduction. Non-small cell lung cancer (NSCLC) takes up 80% of all lung cancer cases and is the most common type of human lung cancer. 1 Although surgery, radiotherapy, and chemotherapy have great progress, the 5-year survival rate of NSCLC patients is still less than 19% due to relapse and drug resistance, and the lack of sensitive and efficient early … WebApr 29, 2024 · The enclosed configuration of circRNAs protects them from degradation and potentiates them as biomarkers. Several circRNAs such as circMUC16, circRNA_MYLK, circRNA-UBAP2, circWHSC1, hsa_circ_0013958, circFGFR3, hsa_circRNA_102958 and circ_0072995 have been found to be up-regulated in this cancer, acting as oncogenes. how to see upvotes reddit
CircWHSC1 serves as an oncogene to promote hepatocellular carcinoma ...
WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues. WebAug 8, 2024 · 2693 Hilltop Rd, Clermont, FL 34711. 11514 Beaman Cir, Clermont, FL 34711. 10001 Crenshaw Cir, Clermont, FL 34711 is a 3 bedroom, 2 bathroom, 2,074 sqft … WebDec 31, 2024 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate … how to see uptime windows 10