WebDec 4, 2024 · Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer Authors WebPage 7/10 Safety Data Sheet acc. to OSHA HCS Printing date 09/09/2024 Revision date 09/09/2024 Trade name:Cisplatin (Contd. from page 6) 53.1.21 · Primary irritant effect: · on the skin:No irritant effect. · on the eye:Strong irritant with the danger of severe eye injury. · Sensitization: Sensitization possible through inhalation.
Chemotherapy Agents and Infertility – Oncofertility …
WebApr 10, 2024 · Multiple studies over time demonstrate that surgery involving the reproductive organs, radiation to gonadal tissue and the hypothalamus, and chemotherapy agents that diminish reproductive germ cells impair fertility [6, 7, 8, 9].Infertility related to germ cell loss by radiation or chemotherapy in both males and females results from a significant and … WebSep 1, 2024 · Cisplatin for injection has been administered at 50 mg/m 2 to 70 mg/m 2 intravenously per cycle once every 3 to 4 weeks. For heavily pretreated patients, an … how many diamonds exist
Impacts of platinum-based chemotherapy on subsequent …
Webfertility in females certainly declines in the last 2 decades prior to menopause (according to the American Society of Reproductive Medicine, most women in their mid-40’s are unable to have successful pregnancies);1 in addition, amenorrhea or azoospermia may result from stress to the body, such as during acute illness. For example, 54% of WebDec 21, 2024 · Cisplatin is a potent first-line of chemotherapeutic drug for treating various neoplasms, but its administration in hospital settings is hampered due to its untoward nephrotoxicity. Previous investigations indicated that about 30% of cisplatin-treated patients (at the dose of 50–100 mg/m 2) developed AKI [ 7 ]. WebMar 22, 2016 · New study looks at how chemo affects childhood cancer survivors’ ability to have kids later in life. A new Fred Hutch study looked at chemotherapy's impact on the fertility of young cancer patients later in life. Women fared better, for the most part, with about 70 percent of survivors able to have kids. Men were significantly less likely to ... high temperament