Web19 apr. 2024 · In this study, we describe the identification and characterization of Fbxl8, an F-box protein that has only just recently been shown to function as an E3 ubiquitin … Web15 dec. 1991 · It is demonstrated that Pak2 phosphorylates Myc at three sites (T358, S373, and T400) and affects Myc functions both in vitro and in vivo, suggesting that inhibition of Myc plays a role in the cellular response to stress, and raising the possibility thatPak2 may be the product of a tumor suppressor gene. 76 PDF View 1 excerpt, cites background
Site-specific modulation of c-Myc cotransformation by residues ...
Web1 jan. 1994 · c-Myc is a nuclear phosphoprotein which binds DNA as a heterodimer with Max. We have identified two in vivo phosphorylation sites, Thr58 and Ser62, within a … WebPhosphoSitePlus ® is an online systems biology resource for information and tools related to the study of post-translational modifications (PTMs), including phosphorylation, ubiquitination, acetylation, and methylation. Created with grant support from the NIH and … dishrag pickles recipe easy
BRD4 and MYC: power couple in transcription and disease
Web15 dec. 2016 · YAP phosphorylation at Ser127 site increases its binding with 14-3-3 and results in cytoplasmic retention 15 20. Here, we observed that although osmotic stress … Web17 nov. 2006 · Thus phosphorylation of Thr-58 appears to be strictly dependent on prior phosphorylation of Ser-62. Similar findings were made for MYCN (36). … WebMYC - Sequence 1 GENE 2 ISO 2138 REF Gold Only Extend overview MYC → Myc proto-oncogene protein Protein also known as : Class E basic helix-loop-helix protein 39 (bHLHe39) . Gene name : MYC Entry whose protein (s) existence is based on evidence at protein level. Displayed isoform: Iso 1 Change isoform FILTER All/None dish rag vs tea towel